Description
xWhat Is Amaryl M SR Tablets 1mg/500mg?
Amaryl M SR 1/500 combines Glimepiride 1mg with Metformin 500mg in a sustained-release tablet, made by Sanofi-Aventis Pakistan. It treats type 2 diabetes in adults who need both medicines. This medicine requires a prescription.
How It Works
Glimepiride increases insulin release from the pancreas, while metformin reduces sugar production by the liver and helps the body respond better to insulin. The sustained-release metformin is released gradually, which is gentler on the stomach.
Uses
Type 2 diabetes not adequately controlled with glimepiride or metformin alone, or for patients already taking both separately.
Dosage
Usually one tablet once or twice daily with meals, as prescribed. Swallow whole; do not crush or chew the sustained-release tablet. Your doctor may move to Amaryl M SR 2/500 if more control is needed.
Side Effects
Low blood sugar (from glimepiride), and stomach upset, diarrhoea, nausea or a metallic taste (from metformin), which usually settle. Long-term metformin can lower vitamin B12. Lactic acidosis is very rare but serious: seek help for severe muscle pain, rapid breathing, stomach pain and unusual tiredness.
Precautions
Not for type 1 diabetes, severe kidney or liver disease, heart failure with poor circulation, or heavy alcohol use. Stop temporarily before X-ray contrast dye or surgery as your doctor advises. Kidney function and blood sugar need regular checks. Store below 30°C.
Common Questions
Why is it called SR? SR means sustained release: the metformin part is released slowly through the day.
Can I break the tablet? No, swallow it whole to keep the slow-release effect.
Single-ingredient option: Amaryl 1mg. Browse more in our Diabetes Medicines collection.
Delivery & Returns
xDelivery
- We deliver across Pakistan: usually 1–2 business days to major cities and 3–5 business days elsewhere.
- Free delivery on orders above Rs 15,000; a flat Rs 450 delivery charge applies to smaller orders.
- Cash on Delivery is available in Sindh. Elsewhere in Pakistan, pay by bank transfer or card.
- Insulin, vaccines and other cold-chain medicines are shipped in insulated packaging with cool packs.
Returns and refunds
- If an item arrives damaged, expired, defective, wrong or missing, tell us within 48 hours of delivery and send photos of the item and packaging.
- For your safety, opened medicines, dispensed prescription medicines and change-of-mind returns cannot be accepted.
- Approved refunds are processed within 7–10 business days, or as store credit for Cash on Delivery orders.
See our full Shipping Policy and Refund Policy.
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