Description
xWhat Is Amaryl M SR Tablets 2mg/500mg?
Amaryl M SR 2/500 contains Glimepiride 2mg and sustained-release Metformin 500mg, made by Sanofi-Aventis Pakistan. It is a two-in-one tablet for adults with type 2 diabetes. This medicine requires a prescription.
How It Works
Two complementary actions: glimepiride boosts insulin release, and metformin lowers glucose output from the liver and improves insulin sensitivity. Together they control blood sugar better than either alone.
Uses
Type 2 diabetes in adults who need more control than Amaryl M SR 1/500 or single medicines provide.
Dosage
Take with meals, usually once or twice daily as directed by your doctor. Swallow whole without crushing. Do not skip meals after taking it.
Side Effects
Hypoglycaemia (sweating, shaking, hunger, confusion), digestive upset such as nausea, diarrhoea or bloating, metallic taste and, over the long term, low vitamin B12. Very rarely, lactic acidosis may occur and needs emergency care.
Precautions
Not for type 1 diabetes, ketoacidosis, significant kidney or liver impairment, severe infection, dehydration or heavy alcohol use. Your doctor will pause it around surgery or contrast scans. Regular kidney function, sugar and HbA1c checks are needed. Not for use in pregnancy. Store below 30°C.
Common Questions
What is the difference between Amaryl and Amaryl M? Amaryl contains only glimepiride; Amaryl M adds metformin in the same tablet.
Should I take it with food? Yes, always with a meal to reduce stomach upset and low sugar risk.
Browse more in our Diabetes Medicines collection, or see Amaryl 2mg.
Delivery & Returns
xDelivery
- We deliver across Pakistan: usually 1–2 business days to major cities and 3–5 business days elsewhere.
- Free delivery on orders above Rs 15,000; a flat Rs 450 delivery charge applies to smaller orders.
- Cash on Delivery is available in Sindh. Elsewhere in Pakistan, pay by bank transfer or card.
- Insulin, vaccines and other cold-chain medicines are shipped in insulated packaging with cool packs.
Returns and refunds
- If an item arrives damaged, expired, defective, wrong or missing, tell us within 48 hours of delivery and send photos of the item and packaging.
- For your safety, opened medicines, dispensed prescription medicines and change-of-mind returns cannot be accepted.
- Approved refunds are processed within 7–10 business days, or as store credit for Cash on Delivery orders.
See our full Shipping Policy and Refund Policy.
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